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multinational Journal of
molecular Sciences
ISSN 1422-0067 www.mdpi.com/ diary/ijms Review
The Role of Molecular Biology in the Biomonitoring of Human photograph to Chemicals
Balam Muñoz and Arnulfo Albores * Departamento de ToxicologÃa, Centro de Investigación y de Estudios Avanzados del IPN, Av. IPN 2508, México, DF 07360, Mexico; E-Mail: rbmunoz@cinvestav.mx * Author to whom concord should be addressed; E-Mail: aalbores@cinvestav.mx; Tel.: +52-55-50613308; Fax: +52-55-57477111. Received: 1 September 2010; in revised form: 12 October 2010 / sure: 29 October 2010 / Published: 12 November 2010
Abstract: Exposure to divergent substances in an occupational environment is of utmost concern to planetary agencies such as the World Health Organization and the International Labour Organization. Interest in improving work wellness conditions, particularly of those employees exposed to noxious chemical substances, has increased considerably and has stirred the search for new, more specific and selective tests. Recently, the field of molecular biology has been indicated as an alternative technique for monitoring force play while evaluating work-related pathologies.
Originally, occupational exposure to environmental toxicants was assessed using biochemical techniques to determine the presence of higher concentrations of toxic compounds in blood, urine, or other fluids or tissues; results were used to evaluate potential wellness risk. However, this approach only estimates the presence of a noxious chemical and its effects, but does not prevent or diminish the risk. Molecular biology methods have become very useful in occupational medicine to provide more accurate and well-timed(prenominal) diagnostics. In this review, we discuss the role of the following common techniques: (1) routine of cell cultures; (2) evaluation of gene expression; (3) the omic sciences (genomics, transcriptomics, proteomics and...If you want to grow a full essay, order it on our website: Orderessay
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